Assuntos
Proteínas de Bactérias/análise , Infecções por Klebsiella/diagnóstico , Klebsiella pneumoniae/enzimologia , Klebsiella pneumoniae/isolamento & purificação , Mediastinite/diagnóstico , Osteomielite/diagnóstico , Infecção da Ferida Cirúrgica/diagnóstico , beta-Lactamases/análise , Idoso , Eletroforese em Gel de Campo Pulsado , Feminino , Genótipo , Humanos , Infecções por Klebsiella/microbiologia , Klebsiella pneumoniae/classificação , Klebsiella pneumoniae/genética , Mediastinite/microbiologia , Tipagem de Sequências Multilocus , Osteomielite/diagnóstico por imagem , Osteomielite/microbiologia , Radiografia Torácica , Cintilografia , Recidiva , Esterno/patologia , Infecção da Ferida Cirúrgica/microbiologia , Cirurgia TorácicaRESUMO
Catch-up or compensatory growth is known as a physiological phenomenon. However, most studies of catch-up growth were based on measurements of body weight, whereas changes in longitudinal bone growth remained largely undescribed. The present study describes the dynamics of both weight and longitudinal bone growth using mikro-knemometry, during normal feeding, severe food restriction (starvation), and refeeding of 14 intact and 28 GH-deficient male rats. Starvation induced rapid weight loss (P < 0.001), and stunted leg growth (P < 0.001). Refeeding led to rapid catch-up in weight of up to 4 times above normal daily weight gain, both in intact and GH-deficient animals, whereas an equivalent compensation of lower leg growth remained undetectable. Intact and GH-deficient animals show a circaseptan spontaneous variation of growth velocity (mini growth spurts). During starvation, mini growth spurts disappear, and return to normal after refeeding with no evidence of catch-up. In GH-deficient animals, GH (1 IU/rat, administered twice daily s.c. at 10:00 hand 16:00 h) was capable of augmenting catch-up in weight and, to a lesser extent, in leg length increment.
Assuntos
Peso Corporal/fisiologia , Desenvolvimento Ósseo/fisiologia , Inanição/fisiopatologia , Fenômenos Fisiológicos da Nutrição Animal , Animais , Peso Corporal/efeitos dos fármacos , Hormônio do Crescimento/sangue , Hormônio do Crescimento/deficiência , Hormônio do Crescimento/farmacologia , Membro Posterior/crescimento & desenvolvimento , Fator de Crescimento Insulin-Like I/metabolismo , Masculino , Ratos , Ratos Wistar , Glutamato de Sódio/toxicidadeRESUMO
Prevalence of gallstone disease in Mexico is similar to that found in some European countries. Patients from those industrialized Western countries primarily develop cholesterol gallstones; however, we do not have information related to the chemical composition of gallstones in the Mexican population. The aim of this study was to determine the physiochemical characteristics of gallstones from patients undergoing surgery for symptomatic cholelithiasis. We analyzed gallstone specimens from 59 patients (17 male and 42 female) from five Mexican states and Mexico City by X-ray diffraction. The chemical analysis revealed that 71.2% of the patients had stones of mixed composition. We concluded that the chemical composition of gallstones found in Mexican patients is similar to that found in patients from other Western countries.
